Ast Alt Ratio Calculator
This De Ritis (AST/ALT) ratio calculator computes the ratio and presents interpretation guidance by range. The page e...
What Ast Alt Ratio Calculator does
The Ast Alt Ratio Calculator on Calc4Lab computes the De Ritis ratio by dividing a user's AST value by their ALT value, both entered in U/L. The result is displayed alongside a reference guide that categorizes the ratio into three clinical ranges: above 2.0 suggests alcoholic liver disease or cirrhosis, approximately 1.0 indicates viral hepatitis or NASH, and below 1.0 points to other chronic liver conditions. The tool also flags very high enzyme levels (>1000 U/L) as potentially indicating acute viral or toxic hepatitis regardless of the ratio. Beyond the calculation, the site emphasizes clinical context, explaining the biological difference between ALT (liver-specific) and AST (found in heart and muscle), and offers links to related lab calculators for broader health assessments.
How to use the Calc4Lab Ast Alt Ratio Calculator
- 1
Enter the AST value in U/L into the first field
- 2
Enter the ALT value in U/L into the second field
- 3
Click 'Calculer le résultat' to compute the ratio
- 4
View the result and the associated interpretation guide based on the calculated range
- 5
Review the clinical context notes about enzyme specificity and patient history before drawing conclusions
Best for
This option suits patients, students, or clinicians who need a quick, reference-backed interpretation of an AST/ALT ratio without manually calculating the division and memorizing the clinical ranges.
Limitations
- Results are estimates and require integration with patient history and symptoms
- The ratio is most useful for moderate transaminase elevations, not very high levels (>1000 U/L)
- No unit switching available; values must be entered in U/L
Ast Alt Ratio Calculator FAQ
- What does a De Ritis ratio greater than 2.0 indicate?
- A ratio greater than 2.0 is very evocative of alcoholic hepatitis or cirrhosis, as alcohol reduces ALT synthesis more than AST.
- What is the typical ratio range for viral hepatitis?
- A ratio approximately equal to 1.0 is typical of acute viral hepatitis or non-alcoholic steatohepatitis (NASH).
- What does a ratio less than 1.0 suggest?
- A ratio less than 1.0 is often observed in other chronic liver diseases where inflammation predominates.
- Are very high AST and ALT levels significant regardless of the ratio?
- Yes, very high levels of AST/ALT (greater than 1000 U/L) typically orient toward acute viral or toxic hepatitis, regardless of the calculated ratio.
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